| Johann Oecolampadius is born. | Magisterial Reformation |
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| Cardinal Ximenez is appointed vicar- general of Siguenza. | Ximenez |
Reformation Happens |
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| April 18 | Bishop Albert of Bavaria calls for a synod in Strasbourg to address issues of reform. Johann Geiler von Kaysersberg serves as official preacher. | Reformation Happens |