| Fall of the Aztecs to Cortes. | |||
| Pope Adrian VI elected. | Catholic Reformation |
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| Ulrich Zwingli defends those who eat meat during Lent. | Zwingli |
Magisterial Reformation |
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| Ulrich Zwingli secretly marries Anna Rhinehardt. | Zwingli |
Magisterial Reformation |
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| Ignatius Loyola spends a year at Manresa. | Loyola |
Catholic Reformation |
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| Bartolome de las Casas becomes a Dominican. | Catholic Reformation |
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| Cajetan sent by pope Adrian VI as legate to Hungary. | Cajetan |
Catholic Reformation |
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| Heinrich Bullinger receives MA from University of Cologne. | Bullinger |
Magisterial Reformation |
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| Karlstadt publishes *A Sermon on the Condition of the Souls that Believe in Christ* which denies the existence purgatory. | Karlstadt |
Radical Reformation |
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| January 19 | Karlstadt marries Anna von Mochau. | Karlstadt |
Radical Reformation |