| Conrad Grebel dies of the plague. | Radical Reformation |
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| Menno Simons begins to have doubts about transubstantiation. | Simons |
Radical Reformation |
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| Balthasar Hübmaier begins productive ministry in Nikolsburg. | Hübmaier |
Radical Reformation |
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| Charles V marries Princess Isabella of Portugal. | |||
| Heinrich Bullinger celebrates reformed eucharist at Cistercian monastery. | Bullinger |
Magisterial Reformation |
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| First Diet of Speyer. | Catholic Reformation Magisterial Reformation |
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| Joachim Vadian becomes mayor of St Gall. Later that year, St Gall becomes a reformed city. | Vadian |
Magisterial Reformation |
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| Ulrich Zwingli and Berchtold Haller attend the Baden Disputation. | Haller Zwingli |
Magisterial Reformation |
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| Henry VIII begins courting Anne Boleyn. | Henry |
English Reformation |
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| Wolsey summons Thomas Bilney and he is forced to take an oath not to disseminate Luther's views. | Bilney |
Catholic Reformation English Reformation |
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| April 21 | Schwenckfeld suggests in a letter circulated among his followers that advocates the suspension of the Lord's Supper. | Schwenckfeld |
Radical Reformation |
| August 29 | Battle of Mohács. [More] | ||
| December 25 | Hans Denck is expelled from Strasbourg. | Radical Reformation |
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| December 25 | Hans Denck is expelled from Strasbourg. | Radical Reformation |